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Clinically Proven to Help You Lose Weight

yerba mateOur herbal supplement is certainly a cut above the rest. Made from a unique formulation of 3 natural plant extracts – Yerba Mate, Guarana and Damiana (YGD) – Zotrim is the only non-medical proven weight loss product on the market to be confirmed as a “weight loss aid with sound scientific proof.“

Since we first launched Zotrim in 2000, our supplement has successfully undergone 8 clinical studies and has made appearances at the 15th European Congress on Obesity, the British Food Journal and in the Journal of Human Nutrition and Dietetics.

We want you to feel confident in the usability of our supplement and we feel our studies can offer you that reassurance.

Below we have included all our completed studies to enable you to see why with Zotrim… you’ll always feel full of life:

  1. Placebo-controlled study on weight loss
  2. Conducted over a 45 day period, 47 overweight subjects aged between 20 and 60 were given Zotrim to assess the effects Zotrim’s formulation had on their weight loss. Split into groups consisting of those on Zotrim and those taking a placebo capsule containing lactose, they were instructed to take their capsules 3 times a day before every meal.

  • Zotrim: lost on average 11.3 lbs
  • Placebo: 0.7lbs

Investigator: Torben Anderson
Published: Journal of Human Nutrition and Dietetics, 2001

  1. Effect on weight maintenance
  2. Designed to examine Zotrim’s ability to help consumers maintain their weight loss, 22 of the 24 subjects who took part in the above study by Torben Andersen, were provided with a 12 month supply of Zotrim. Weighed monthly, they were instructed to take Zotrim if they started to put weight back on

  • Start of study: average weight 161lbs
  • End of 12 month study: average weight 160lbs

Investigator: Torben Anderson
Published: Journal of Human Nutrition and Dietetics, 2001

  1. Consumer study on weight loss and eating behaviour
  2. Performed using 50 UK adults who wished to lose weight, they were provided with Zotrim capsules and were instructed to take 2 tablets, 3 times a day before every meal.

    Over the course of a month, they had to complete questionnaires based on their progress for the time leading to day 7, 14 and 28.

  • Average weight loss: 5.5lbs in 28 days
  • 50% reported to have eaten less than usual
  • 66% reported to have snacked less between meals

Investigator: Carrie Ruxton
Published: Nutrition & Food Science, 2004

  1. Gastric emptying rate study
  2. In order to assess the connection between stomach fullness and gastric emptying, 7 subjects - who had previously fasted prior to the study – were given Zotrim formulation on one occasion and placebo capsules of lactose on another occasion in a double blinded study.

    Asked to drink 20ml of apple juice followed 15 minutes later by a further 400ml, their gastric volume was monitored through ultrasound measurement every 10 minutes until their stomachs had emptied.

  • Zotrim: average gastric emptying 58 minutes
  • Placebo: average gastric emptying 38 minutes

Investigator: Jan Fogh
Published: Journal of Human Nutrition and Dietetics, 2001

  1. Time to fullness study
  2. The time needed to achieve gastric fullness was investigated using 20 subjects who were asked to take 2 capsules of Zotrim or 2 of the lactose placebo capsules. Instructed to take them 10-15 minutes before every main meal, whilst they ate they had to monitor the length of time it took for them to feel full. This figure was then compared to their other meals.

  • Zotrim: Average combined time to gastric fullness over 3 meals: 35 minutes
  • Placebo: Average combined time to gastric fullness over 3 meals: 61 minutes

Investigator: Torben Anderson
Published: 3rd Health and Nutrition Conference, 2002

  1. Effect of TV Viewing and Zotrim on snacking
  2. Identified as a key influencing factor behind out eating choices and weight management, the effect of TV viewing and Zotrim on subjects energy intake was explored with the help of 11 healthy adults.

    Split into 2 groups, subjects were required to either take 2 Zotrim tablets or 2 placebo tablets in the morning as well as before lunch. 2 hours after eating, subjects were then exposed to a TV video or a blank screen were given the additional option of either reading/studying or having unlimited access to sugary foods. Their total energy intake during lunch and snacking was then measured.

  • Zotrim: energy intake dramatically reduced when watching TV
  • Placebo: energy intakes was significantly higher when subjects watched TV than when they chose not to

Investigator: G Baker and AR Leeds, Department of Nutrition & Dietetics
Published: 3rd Health and Nutrition Conference, 2002

  1. Weight Loss Study
  2. During a customer intervention, 61 overweight women took Zotrim for a period of 4 weeks. From here their hunger and eating patterns were recorded, whilst their weight loss and waist measurements were also taken at the beginning of the study, during week 2 and lastly on week 4.

  • Average weight loss: 4lbs in 6 weeks
  • Average waist reduction: 4.3cm in 4 weeks
  • Subjects consistently felt fuller for longer
  • Changes witnessed through Zotrim over these 4 weeks compared favourably with long term weight management therapies

Investigator: C.H.S Ruxton, F Hinton and C.E.L Evans
Published: Nutrition and Food Science, 2005

  1. Study with healthcare professionals
  2. 70 healthcare professionals were asked to take Zotrim for 6 weeks during an ‘open label’ study. In this time they experienced:

  • Average weight loss: 5.06lbs in 6 weeks
  • Average waist reduction: 3.4 cm
  • Reported increased satiety after meals
  • Reported decreased snacking and hunger between meals
  • 22% lost more than 5% of their original weight

Investigator: C.H.S Ruxton, I. Kirkwood, B. McMillan and C.E.L Evans
Published: British Food Journal, 2007


Our supplement may have only been around for less than a decade, but the strength of our evidence has resulted in numerous publications across an array of medical journals.

Below we have listed our 5 most recent publications to help give you a closer look into the inner workings of our supplement.

  1. “Impact of a herbal supplement on control of eating and body weight” – poster presented at the 15th European Congress on Obesity, April 2007

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  2. Most Important: “Weight loss and delayed gastic emptying following a South American herbal preparation in overweight patients”

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    Most recent: “Early Sensation of Gastric Fullness following a herbal preparation used for weight loss” – Torben S Anderson, November 2002

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  3. “Energy intake from snacks wile viewing television, and the effect on this of a herbal preparation” – Baker & Leeds, Department of Nutrition & Diabetics, 2002

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  4. “Efficiency of Zotrim: a herbal weight loss preparation” – Ruxton, Nutrition & Food Science, 2004

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  5. “Effectiveness of a herbal supplement (Zotrim) for weight management” – British Food Journal, 2007

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  6. “Effects of an over-the-counter herbal weight management product (Zotrim) on weight and waist circumference in a sample of overweight women” – C.H.S Ruxton, F. Hinton, C.E.L Evans, 2005

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